Psychopharmacology: A Biochemical and Behavioral Approach

Format: Hardcover

Language: English

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Continuous large doses of a corticosteroid adversely affect collagen synthesis, and, therefore, connective tissue strength. [6, 7] Frequency of injections and dosages must be monitored by the practitioner to prevent generalized or focal immune suppression such as infection or impaired soft tissue healing. [3] Therefore, the amount of corticosteroids that can be applied over time to a specific tissue area can be detrimental, although the exact dose/time curve remains unknown. [3] Concomitant use of medications that alter corticosteroid effects or clearance is usually not salient when injections are provided intermittently.

Pages: 451

Publisher: Van Nostrand Reinhold; First Edition edition (June 1977)

ISBN: 0442274815

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